Home DNA Damage/DNA Repair -Epigenetics PARP Tankyrase-1 Inhibitors

Tankyrase-1 Inhibitors

  • PARP1
  • PARP2
  • PARP3
  • Tankyrase-1
Nº Cat. Nombre del producto Información Selectivo / Pan IC50 / Ki
S1060 Olaparib (AZD2281, Ku-0059436) Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM, 300-times less effective against tankyrase-1. Phase 3. Pan Tankyrase-1, IC50: 1.5 μM