Home Proteases -Ubiquitin Proteasome Proteasome-Selectivo Inhibitors

Proteasome-Selectivo Inhibitors

  • Proteasome
  • 20S proteasome
Nº Cat. Nombre del producto Información Selectivo / Pan IC50 / Ki
S2853 Carfilzomib (PR-171) Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities. Selective Proteasome, IC50: 5 nM
S2619 MG-132 MG-132 is an inhibitor of proteasome with IC50 of 100 nM, and also inhibits calpain with IC50 of 1.2 μM. Selective Proteasome, IC50: 100 nM