Home Metabolism -DNA Damage/DNA Repair PPAR PPARα-Selectivo Activators | Agonists | Antagonists

PPARα-Selectivo Activators | Agonists | Antagonists

  • PPARα
  • PPARβ/δ
  • PPARγ
  • PPARδ
Nº Cat. Nombre del producto Información Selectivo / Pan IC50 / Ki
S8029 WY-14643 (Pirinixic Acid) WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with EC50 of 1.5 μM. Selective PPARα, EC50: 1.5 μM
S4207 Clofibric Acid Clofibric acid is a PPARα agonist and hypolipidemic agent. Selective
S1729 Gemfibrozil Gemfibrozil (Lopid) is a compound used to lower lipid levels. Selective
S1794 Fenofibrate Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative. Selective
S2915 GW9662 GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ. Pan PPARα, IC50: 32 nM
S2871 T0070907 T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity over PPARα and PPARδ. Pan PPARα, IC50: 0.85 μM