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HD1-Selectivo Inhibitors

Nº Cat.	Nombre del producto	Información	Selectivo / Pan	IC50 / Ki
S1484	MC1568	MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM. It is 34-fold more selective for HD1-A than HD1-B.	Selective	HD1-B (Maize), IC50: 3.4 μM; HD1-A (Maize), IC50: 100 nM
S2170	Givinostat (ITF2357)	Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM. Phase 2.	Pan	HD1-B, IC50: 7.5 nM; HD1-A, IC50: 16 nM