ERK2 Inhibitors
- ERK1
- ERK2
- ERK5
| Nº Cat. | Nombre del producto | Información | Selectivo / Pan | IC50 / Ki |
|---|---|---|---|---|
| S7554 | GDC-0994 | GDC-0994 is a potent, orally available ERK1/2 inhibitor with IC50 of 1.1 nM and 0.3 nM, respectively. Phase 1. | Pan | ERK2, IC50: 0.3 nM |
| S7101 | SCH772984 | SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. | Pan | ERK2, IC50: 1 nM |
| s7524 | FR 180204 | FR 180204 is an ATP-competitive, selective ERK inhibitor with Ki of 0.31 μM and 0.14 μM for ERK1 And ERK2, respectively. | Pan | ERK2, Ki: 0.14 μM |
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