Home GPCR & G Protein -Neuronal Signaling Cannabinoid Receptor CB2-Selectivo Agonists | Antagonists

CB2-Selectivo Agonists | Antagonists

  • CB1
  • CB2
Nº Cat. Nombre del producto Información Selectivo / Pan IC50 / Ki
S1544 AM1241 AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Selective CB2, Ki: 3.4 nM
S2778 GW842166X GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase 2. Selective CB2, EC50: 63 nM
S2854 BML-190 BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor. Selective CB2, Ki: 435 nM
S3021 Rimonabant Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Pan hCB2, IC50: 1.64 μM
S8012 Otenabant (CP-945598) HCl Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1. Pan hCB2, Ki: 7.663 μM